Garlic Butter Shrimp Scampi Lasagna Recipe
If you’re looking for a show-stopping twist on classic comfort food, this Garlic Butter Shrimp Scampi Lasagna is about to become your new favorite. Imagine the best parts of shrimp scampi—plump, garlicky shrimp bathed in a velvety butter sauce—cozily layered between sheets of tender pasta, all lusciously enveloped in a cheesy, creamy sauce. It’s a dish that feels effortlessly elegant but is perfect for any family dinner or special occasion. Every bite bursts with layers of rich flavor and stunning textures, making this lasagna an absolute must-try for seafood and pasta lovers alike.

Ingredients You’ll Need
This recipe is all about simple, wholesome ingredients working together to create something truly spectacular. Each one brings color, texture, and layers of flavor that make this Garlic Butter Shrimp Scampi Lasagna completely irresistible.
- Lasagna noodles: Go for classic or oven-ready noodles; they become perfectly tender and hold all those delicious layers together.
- Large shrimp, peeled and deveined: The star of the show—they soak up the garlicky butter, adding succulence to every bite.
- Garlic, minced: You’ll use plenty; it infuses both the shrimp and the sauce with vibrant aroma and flavor.
- Butter: Adds creamy richness to both the shrimp and the savory sauce—it’s what makes the scampi shine.
- All-purpose flour: Helps thicken the white sauce so it’s luxuriously creamy but never heavy.
- Milk: The foundation of your béchamel, giving the sauce a silky texture.
- Grated Parmesan cheese: Adds a nutty, salty depth that balances the creaminess of the sauce.
- Shredded mozzarella cheese: Melts beautifully for that golden-bubbly, cheesy topping.
- Fresh parsley, chopped: Brings a splash of color and a finishing pop of freshness.
- Salt and pepper: Essential for brightening all the flavors.
- Lemon juice: Lifts the entire dish with a zesty accent that pairs perfectly with seafood.
How to Make Garlic Butter Shrimp Scampi Lasagna
Step 1: Cook the Lasagna Noodles
Start by boiling the lasagna noodles according to the package directions until they’re just al dente. They’ll continue cooking in the oven, so you don’t want them too soft. Drain and lay them flat on a clean towel to prevent sticking—they’re now ready for layering magic.
Step 2: Sauté the Garlic and Shrimp
Melt butter in a large skillet over medium heat, then stir in the minced garlic. Let it become aromatic—there’s nothing better. Add your shrimp and cook them for 2–3 minutes per side until they’re brilliantly pink and opaque. Be careful not to overcook! Remove the shrimp and set them aside—you’ll be layering them soon.
Step 3: Prepare the Garlic Butter Sauce
Using the same skillet (hello, easy cleanup!), melt more butter and add fresh garlic. Cook until fragrant, then sprinkle in the flour. This simple step forms a quick roux, which acts as the base for your creamy sauce, thickening it to dreamy perfection.
Step 4: Make the White Sauce
Gradually whisk in the milk so your sauce is smooth and lump-free. Stir it gently as it simmers and thickens, then take it off the heat and fold in the Parmesan cheese until it’s completely melted. Give the sauce a taste—season with salt, pepper, and a hit of lemon juice for that trademark scampi brightness.
Step 5: Layer the Lasagna
Preheat your oven to 375°F. In your chosen baking dish, spread a thin layer of garlic butter sauce on the bottom, then top with lasagna noodles. Add more sauce, scatter shrimp, sprinkle mozzarella, and repeat the sequence. Continue layering until you’ve used everything, finishing with a generous crown of sauce and mozzarella for maximum gooeyness.
Step 6: Bake to Golden Perfection
Cover the lasagna tightly with foil and bake for 25 minutes. Remove the foil and bake another 10 minutes so the cheese gets those irresistible golden-brown edges and melts into the layers. Let the lasagna rest for a few minutes before slicing to help the layers set.
Step 7: Garnish and Serve
Top your masterpiece with a sprinkle of chopped parsley before serving. The freshness from the herbs brightens every bite and makes your Garlic Butter Shrimp Scampi Lasagna look extra inviting.
How to Serve Garlic Butter Shrimp Scampi Lasagna

Garnishes
A flourish of fresh parsley or even a fine grating of lemon zest over the top adds color and sharpens the flavors. For an extra bit of luxury, drizzle a touch more melted butter over each portion just before serving—this makes every bite taste even silkier.
Side Dishes
This decadent lasagna loves something light on the side. Fresh green salads with a lemony vinaigrette, crisp roasted asparagus, or simple steamed broccoli all make fantastic companions. And if you’re a bread lover, some crusty garlic bread is practically non-negotiable for mopping up all that luscious sauce.
Creative Ways to Present
For a special occasion, try baking the Garlic Butter Shrimp Scampi Lasagna in individual ramekins—everyone gets their own personal mini-lasagna (and lots of crispy edges). Or, cut the lasagna into small squares and serve as part of a festive pasta buffet alongside classic Italian favorites—your guests will absolutely swoon.
Make Ahead and Storage
Storing Leftovers
Leftover Garlic Butter Shrimp Scampi Lasagna stores beautifully in the fridge. Once cooled, transfer slices to an airtight container and refrigerate for up to three days—the flavors actually meld and deepen, making the next-day leftovers something to look forward to.
Freezing
You can absolutely freeze this lasagna for later! Assemble the lasagna (but don’t bake it), wrap it tightly in plastic wrap and foil, and pop it in the freezer for up to 2 months. When you’re ready to serve, thaw completely in the fridge before baking as usual for that fresh-from-the-oven experience.
Reheating
For best results, reheat leftovers in a 350°F oven, covered with foil to prevent drying out, until heated through. If you’re in a hurry, individual slices microwave well—just add a splash of milk to keep the sauce creamy and prevent sticking.
FAQs
Can I use pre-cooked shrimp for this recipe?
While fresh, raw shrimp offer the best flavor and texture, you can use pre-cooked shrimp in a pinch. Just gently fold them into the sauce without additional cooking so they don’t become rubbery.
Is it possible to make this lasagna gluten-free?
Absolutely! Replace the lasagna noodles with your favorite gluten-free variety and use a 1:1 gluten-free all-purpose flour for the sauce. You’ll hardly notice the difference—just all the deliciousness.
What’s the best way to prevent watery lasagna?
Be sure to cook the noodles al dente and drain them well before assembling. Letting the lasagna rest after baking also helps the layers set and excess sauce to be absorbed, keeping every piece perfectly sliceable.
Can I add vegetables to this lasagna?
Definitely! Sautéed spinach, zucchini ribbons, or even a handful of cherry tomatoes would be fantastic additions. Just make sure any veggies are cooked and drained well to prevent watering down the sauce.
How do I know if the lasagna is done?
Look for golden, bubbly cheese on top and hot, steamy layers within. If you insert a knife and it comes out hot to the touch, you’re good to go! Let it rest for at least 10 minutes before slicing for beautiful, tidy layers.
Final Thoughts
This Garlic Butter Shrimp Scampi Lasagna is what weeknight dreams and special-occasion dinners are made of—rich, decadent, and full of unbeatable flavors. I hope you try it soon and experience just how much joy a single pan of lasagna can bring to your table. Don’t be surprised if it becomes the most requested dish in your kitchen!
Print
Garlic Butter Shrimp Scampi Lasagna Recipe
- Total Time: 1 hour 5 minutes
- Yield: 8 servings 1x
- Diet: Non-Vegetarian
Description
Indulge in the ultimate comfort food with this luxurious Garlic Butter Shrimp Scampi Lasagna. Layers of tender shrimp, creamy garlic butter sauce, and gooey cheese come together in this decadent twist on classic lasagna.
Ingredients
For the Lasagna:
- 1 box of lasagna noodles
- 1 pound of large shrimp, peeled and deveined
- 4 cloves of garlic, minced
- 1/2 cup of butter
- 1/4 cup of all-purpose flour
- 2 cups of milk
- 1 cup of grated Parmesan cheese
- 1 cup of shredded mozzarella cheese
- 1/4 cup of chopped fresh parsley
- Salt and pepper to taste
For the Garlic Butter Sauce:
- 1/2 cup of butter
- 4 cloves of garlic, minced
- 1/4 cup of chopped fresh parsley
- 1 tablespoon of lemon juice
- Salt and pepper to taste
Instructions
- Cook the lasagna noodles: Cook the lasagna noodles according to the package instructions. Drain and set aside.
- Sauté garlic and shrimp: In a large skillet, melt the butter over medium heat. Add the minced garlic and cook until fragrant. Add the shrimp and cook until pink and opaque. Remove the shrimp from the skillet and set aside.
- Prepare the garlic butter sauce: In the same skillet, melt the butter. Add the minced garlic and cook until fragrant. Stir in the flour and cook until well combined. Gradually whisk in the milk and cook until thickened. Remove from heat and stir in Parmesan cheese, salt, and pepper.
- Assemble the lasagna: Preheat the oven. Spread a layer of sauce in a baking dish. Layer lasagna noodles, sauce, shrimp, and mozzarella cheese. Repeat layers and finish with sauce and mozzarella on top.
- Bake: Cover with foil and bake. Remove foil and bake until cheese is golden and bubbly.
- Serve: Let the lasagna cool, garnish with parsley, and serve.
- Prep Time: 20 minutes
- Cook Time: 45 minutes
- Category: Main Dish
- Method: Baking
- Cuisine: Italian
Nutrition
- Serving Size: 1 slice
- Calories: 450
- Sugar: 2g
- Sodium: 700mg
- Fat: 25g
- Saturated Fat: 15g
- Unsaturated Fat: 8g
- Trans Fat: 0g
- Carbohydrates: 35g
- Fiber: 2g
- Protein: 20g
- Cholesterol: 120mg
Keywords: Garlic Butter Shrimp Scampi Lasagna, Shrimp Scampi Lasagna, Garlic Butter Lasagna